Constructive disruption - the act of productively challenging inherited wisdom or structure - supports innovation by opening up the space to replace what we have with what we might imagine.
Training rats to detect landmines and tuberculosis? How could I turn down an opportunity to help develop this innovative solution to such immense worldwide problems?
I remember my grandmother talking about how she cried when Lou Gehrig gave his "luckiest man on the face of the earth" speech at Yankees stadium, announcing that he was going to retire from baseball after being diagnosed with ALS, an illness that would soon become known as Lou Gehrig's disease.